Ontology highlight
ABSTRACT:
SUBMITTER: Li L
PROVIDER: S-EPMC4766031 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Methods (San Diego, Calif.) 20151121
3D organotypic culture models such as organoids and multicellular tumor spheroids (MCTS) are becoming more widely used for drug discovery and toxicology screening. As a result, 3D culture technologies adapted for high-throughput screening formats are prevalent. While a multitude of assays have been reported and validated for high-throughput imaging (HTI) and high-content screening (HCS) for novel drug discovery and toxicology, limited HTI/HCS with large compound libraries have been reported. Non ...[more]