Ontology highlight
ABSTRACT:
SUBMITTER: Sato YT
PROVIDER: S-EPMC4766490 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Sato Yuko T YT Umezaki Kaori K Sawada Shinichi S Mukai Sada-atsu SA Sasaki Yoshihiro Y Harada Naozumi N Shiku Hiroshi H Akiyoshi Kazunari K
Scientific reports 20160225
Exosomes are a valuable biomaterial for the development of novel nanocarriers as functionally advanced drug delivery systems. To control and modify the performance of exosomal nanocarriers, we developed hybrid exosomes by fusing their membranes with liposomes using the freeze-thaw method. Exosomes embedded with a specific membrane protein isolated from genetically modified cells were fused with various liposomes, confirming that membrane engineering methods can be combined with genetic modificat ...[more]