Ontology highlight
ABSTRACT:
SUBMITTER: Binder SC
PROVIDER: S-EPMC4768184 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Binder Sebastian C SC Eckweiler Denitsa D Schulz Sebastian S Bielecka Agata A Nicolai Tanja T Franke Raimo R Häussler Susanne S Meyer-Hermann Michael M
Scientific reports 20160226
The focus of modern molecular biology turns from assigning functions to individual genes towards understanding the expression and regulation of complex sets of molecules. Here, we provide evidence that alternative sigma factor regulons in the pathogen Pseudomonas aeruginosa largely represent insulated functional modules which provide a critical level of biological organization involved in general adaptation and survival processes. Analysis of the operational state of the sigma factor network rev ...[more]