Ontology highlight
ABSTRACT:
SUBMITTER: Cardoso MH
PROVIDER: S-EPMC4768251 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Cardoso Marlon H MH Ribeiro Suzana M SM Nolasco Diego O DO de la Fuente-Núñez César C Felício Mário R MR Gonçalves Sónia S Matos Carolina O CO Liao Luciano M LM Santos Nuno C NC Hancock Robert E W RE Franco Octávio L OL Migliolo Ludovico L
Scientific reports 20160226
Due to the growing concern about antibiotic-resistant microbial infections, increasing support has been given to new drug discovery programs. A promising alternative to counter bacterial infections includes the antimicrobial peptides (AMPs), which have emerged as model molecules for rational design strategies. Here we focused on the study of Pa-MAP 1.9, a rationally designed AMP derived from the polar fish Pleuronectes americanus. Pa-MAP 1.9 was active against Gram-negative planktonic bacteria a ...[more]