Ontology highlight
ABSTRACT:
SUBMITTER: Bahr NC
PROVIDER: S-EPMC4768484 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Bahr N C NC Tugume L L Rajasingham R R Kiggundu R R Williams D A DA Morawski B B Alland D D Meya D B DB Rhein J J Boulware D R DR
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20151001 10
<h4>Background</h4>TB meningitis (TBM) diagnosis is difficult and novel diagnostic methods are needed. The World Health Organization recommends Xpert(®) MTB/RIF as the initial TBM diagnostic test based on two studies reporting suboptimal sensitivity (~50-60%).<h4>Objective</h4>To study the effect of cerebrospinal fluid (CSF) centrifugation on Xpert performance for TBM detection.<h4>Design</h4>A total of 107 predominantly human immunodeficiency virus (HIV) infected adults with presumed meningitis ...[more]