Ontology highlight
ABSTRACT:
SUBMITTER: Nishimura N
PROVIDER: S-EPMC4768783 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Nishimura Naoto N Ueharu Hiroki H Nishihara Hiroto H Shibuya Shiori S Yoshida Saishu S Higuchi Masashi M Kanno Naoko N Horiguchi Kotaro K Kato Takako T Kato Yukio Y
The Journal of reproduction and development 20151206 1
Pituitary-specific transcription factor PROP1, a factor important for pituitary organogenesis, appears on rat embryonic day 11.5 (E11.5) in SOX2-expressing stem/progenitor cells and always coexists with SOX2 throughout life. PROP1-positive cells at one point occupy all cells in Rathke's pouch, followed by a rapid decrease in their number. Their regulatory factors, except for RBP-J, have not yet been clarified. This study aimed to use the 3 kb upstream region and 1st intron of mouse prop1 to pinp ...[more]