Ontology highlight
ABSTRACT:
SUBMITTER: Hao Z
PROVIDER: S-EPMC4769678 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Hao Zheng Z Mumphrey Michael B MB Townsend R Leigh RL Morrison Christopher D CD Münzberg Heike H Ye Jianping J Berthoud Hans-Rudolf HR
Obesity (Silver Spring, Md.) 20160205 3
<h4>Objective</h4>Roux-en-Y gastric bypass surgery (RYGB) results in sustained lowering of body weight in most patients, but the mechanisms involved are poorly understood. The aim of this study was to obtain support for the notion that reprogramming of defended body weight, rather than passive restriction of energy intake, is a fundamental mechanism of RYGB.<h4>Methods</h4>Male C57BL6J mice reaching different degrees of obesity on a high-fat diet either with ad libitum access or with caloric res ...[more]