Ontology highlight
ABSTRACT:
SUBMITTER: Xu R
PROVIDER: S-EPMC4770103 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Xu Rong R Fang Xu-Hao XH Zhong Ping P
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20160223 2
Previously characterized as a backward motor, myosin VI (MYO6), which belongs to myosin family, moves toward the minus end of the actin track, a direction opposite to all other known myosin members. Recent researches have illuminated the role of MYO6 in human cancers, particularly in prostate cancer. However, the role of MYO6 in glioma has not yet been determined. In this study, to explore the role of MYO6 in human glioma, lentivirus-delivered short hairpin RNA (shRNA) targeting MYO6 was designe ...[more]