Ontology highlight
ABSTRACT:
SUBMITTER: Kath JE
PROVIDER: S-EPMC4770218 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Nucleic acids research 20151210 4
Escherichia coli has three DNA polymerases implicated in the bypass of DNA damage, a process called translesion synthesis (TLS) that alleviates replication stalling. Although these polymerases are specialized for different DNA lesions, it is unclear if they interact differently with the replication machinery. Of the three, DNA polymerase (Pol) II remains the most enigmatic. Here we report a stable ternary complex of Pol II, the replicative polymerase Pol III core complex and the dimeric processi ...[more]