Ontology highlight
ABSTRACT:
SUBMITTER: Sharma NK
PROVIDER: S-EPMC4771903 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
International journal of medicinal chemistry 20160216
A new series of Pd (II) complexes of methyl substituted benzylamine ligands (BLs) has been synthesized and characterized via spectroscopic techniques such as UV/Vis. FTIR, LCMS, (1)H, and (13)C NMR. The UV/Vis study in DMSO, DMSO + water, and DMSO + PBS buffer (pH = 7.2) confirmed their molecular sustainability in liquids. Their in vitro anticancer activity against breast cancer cell lines such as MCF-7 and MDA-MB-231 makes them interesting for in vivo analysis. Their stronger DNA binding activi ...[more]