Ontology highlight
ABSTRACT:
SUBMITTER: Tang KT
PROVIDER: S-EPMC4772158 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Tang Kuo-Tung KT Hung Wei-Ting WT Chen Yi-Hsing YH Lin Ching-Heng CH Chen Der-Yuan DY
Scientific reports 20160301
A few studies showed that long-term methotrexate (MTX) use exacerbates liver fibrosis and even leads to liver cirrhosis in rheumatoid arthritis (RA) patients. We therefore conducted a population-based cohort study to investigate the impact of long-term MTX use on the risk of chronic hepatitis B (CHB)-related cirrhosis among RA patients. We analyzed data from the National Health Insurance Research Database in Taiwan and identified 631 incident cases of RA among CHB patients (358 MTX users and 273 ...[more]