Ontology highlight
ABSTRACT:
SUBMITTER: Khosa S
PROVIDER: S-EPMC4773095 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Khosa Sakshi S Hoeppner Astrid A Gohlke Holger H Schmitt Lutz L Smits Sander H J SH
PloS one 20160301 3
Lantibiotics are antimicrobial peptides produced by Gram-positive bacteria. Interestingly, several clinically relevant and human pathogenic strains are inherently resistant towards lantibiotics. The expression of the genes responsible for lantibiotic resistance is regulated by a specific two-component system consisting of a histidine kinase and a response regulator. Here, we focused on a response regulator involved in lantibiotic resistance, NsrR from Streptococcus agalactiae, and determined the ...[more]