Ontology highlight
ABSTRACT:
SUBMITTER: Lin CW
PROVIDER: S-EPMC4773551 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Lin Ching-Wen CW Lin Pei-Ying PY Yang Pan-Chyr PC
Stem cells international 20160216
Epithelial-derived tumor cells acquire the capacity for epithelial-to-mesenchymal transition (EMT), which enables them to invade adjacent tissues and/or metastasize to distant organs. Cancer metastasis is the main cause of cancer-related death. Molecular mechanisms involved in the switch from an epithelial phenotype to mesenchymal status are complicated and are controlled by a variety of signaling pathways. Recently, a set of noncoding RNAs (ncRNAs), including miRNAs and long noncoding RNAs (lnc ...[more]