Impact of Metformin on Advanced Pancreatic Cancer Survival: Too Little, Too Late?
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ABSTRACT:
SUBMITTER: Yang YX
PROVIDER: S-EPMC4775394 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Publications
Impact of Metformin on Advanced Pancreatic Cancer Survival: Too Little, Too Late?
Yang Yu-Xiao YX Rustgi Anil K AK
Clinical cancer research : an official journal of the American Association for Cancer Research 20151204 5
Metformin offers no survival advantage in patients with metastatic pancreatic cancer. Despite promising experimental evidence suggesting an antitumor effect of metformin, its impact on the survival of advanced pancreatic cancer is likely very limited. Future studies may need to consider its role in early-stage pancreatic cancer. See related article by Reni et al., p. 1076. ...[more]
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