Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China.
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ABSTRACT:
SUBMITTER: Lei CW
PROVIDER: S-EPMC4775944 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
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Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China.
Lei Chang-Wei CW Zhang An-Yun AY Wang Hong-Ning HN Liu Bi-Hui BH Yang Li-Qin LQ Yang Yong-Qiang YQ
Antimicrobial agents and chemotherapy 20160111 3
SXT/R391 integrative and conjugative elements (ICEs) were detected in 8 out of 125 Proteus mirabilis isolates from food-producing animals in China. Whole-genome sequencing revealed that seven ICEs were identical to ICEPmiJpn1, carrying the cephalosporinase gene blaCMY-2. Another one, designated ICEPmiChn1, carried five resistance genes. All eight ICEs could be transferred to Escherichia coli via conjugation. The results highlight the idea that animal farms are important reservoir of the SXT/R391 ...[more]
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