Ontology highlight
ABSTRACT:
SUBMITTER: Corbi-Verge C
PROVIDER: S-EPMC4776425 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Cell communication and signaling : CCS 20160302
Protein-protein interactions (PPI) are involved in virtually every cellular process and thus represent an attractive target for therapeutic interventions. A significant number of protein interactions are frequently formed between globular domains and short linear peptide motifs (DMI). Targeting these DMIs has proven challenging and classical approaches to inhibiting such interactions with small molecules have had limited success. However, recent new approaches have led to the discovery of potent ...[more]