Ontology highlight
ABSTRACT:
SUBMITTER: Jarbe TU
PROVIDER: S-EPMC4779682 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Järbe Torbjörn U C TU Gifford Roger S RS Zvonok Alexander A Makriyannis Alexandros A
Behavioural pharmacology 20160401 2-3 Spec Issue
The recent recreational use of synthetic cannabinoid ligands, collectively referred to as 'Spice', has raised concerns about their safety and possible differences in their biological effect(s) from marijuana/Δ-tetrahydrocannabinol (THC). AM2201, a highly efficacious, potent cannabinoid receptor 1 (CB1R) agonist, is a recently detected compound in 'Spice' preparations. Furthermore, structural analogs of AM2201 are now being found in 'Spice'. The present studies were conducted to investigate their ...[more]