Ontology highlight
ABSTRACT:
SUBMITTER: Penick MA
PROVIDER: S-EPMC4780845 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20080716 16
Novel dialkyloxy- and dihydroxyoctahydroperylenes are regioselectively available via a new tandem Friedel-Crafts alkylation of tetrahydronaphthalene precursors followed by oxidative aromatization. Heating of 5-alkyloxy-1-tetralol with p-toluenesulfonic acid in sulfolane gave the corresponding octahydroperylenes in moderate yields. Studies with Lewis acids and tetralin-1,5-diol in acetonitrile at room temperature provided the 4,10-dihydroxy analogue cleanly, albeit in reduced yields. Examples of ...[more]