Ontology highlight
ABSTRACT:
SUBMITTER: Lombardi A
PROVIDER: S-EPMC4781855 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Lombardi Angela A Menconi Francesca F Greenberg David D Concepcion Erlinda E Leo Marenza M Rocchi Roberto R Marinó Michele M Keddache Mehdi M Tomer Yaron Y
Frontiers in endocrinology 20160308
Graves' disease (GD) is an autoimmune oligogenic disorder with a strong hereditary component. Several GD susceptibility genes have been identified and confirmed during the last two decades. However, there are very few studies that evaluated susceptibility genes for GD in specific geographic subsets. Previously, we mapped a new locus on chromosome 3q that was unique to GD families of Italian origin. In the present study, we used association analysis of single-nucleotide polymorphism (SNPs) at the ...[more]