Ontology highlight
ABSTRACT:
SUBMITTER: Sprink T
PROVIDER: S-EPMC4783127 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Science advances 20160304 3
Throughout the four phases of protein biosynthesis-initiation, elongation, termination, and recycling-the ribosome is controlled and regulated by at least one specified translational guanosine triphosphatase (trGTPase). Although the structural basis for trGTPase interaction with the ribosome has been solved for the last three steps of translation, the high-resolution structure for the key initiation trGTPase, initiation factor 2 (IF2), complexed with the ribosome, remains elusive. We determine t ...[more]