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Dynamic reorganization of the actin cytoskeleton.


ABSTRACT: Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations.

SUBMITTER: Letort G 

PROVIDER: S-EPMC4784019 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Dynamic reorganization of the actin cytoskeleton.

Letort Gaëlle G   Ennomani Hajer H   Gressin Laurène L   Théry Manuel M   Blanchoin Laurent L  

F1000Research 20151001


Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of anothe  ...[more]

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