Emergence in Italy of a Neisseria meningitidis clone with decreased susceptibility to penicillin.
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ABSTRACT:
SUBMITTER: Stefanelli P
PROVIDER: S-EPMC478501 | biostudies-literature | 2004 Aug
REPOSITORIES: biostudies-literature
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Emergence in Italy of a Neisseria meningitidis clone with decreased susceptibility to penicillin.
Stefanelli Paola P Fazio Cecilia C Neri Arianna A Sofia Tonino T Mastrantonio Paola P
Antimicrobial agents and chemotherapy 20040801 8
A rise in invasive diseases due to Neisseria meningitidis C:2b:P1.5 with decreased penicillin susceptibility occurred in Italy during the last 2 years. Real-time PCR identified the Peni phenotype, and the penA sequence revealed the mosaicism of the gene. Molecular analyses assigned the isolates to a single emergent clone of the hypervirulent A4 cluster. ...[more]
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