Proteome Analyses of Staphylococcus aureus Biofilm at Elevated Levels of NaCl.
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ABSTRACT:
SUBMITTER: Islam N
PROVIDER: S-EPMC4786021 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
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Proteome Analyses of <i>Staphylococcus aureus</i> Biofilm at Elevated Levels of NaCl.
Islam Nazrul N Ross Julia M JM Marten Mark R MR
Clinical microbiology (Los Angeles, Calif.) 20150922 5
Our studies demonstrate that sodium chloride (NaCl) induces changes in biofilm, mediated by increased production of polysaccharides intercellular adhesion (PIA). We identified 12 proteins that showed higher abundance in increased level of NaCl. This includes one important protein (IsaA) known to be associated with biofilm stability. In addition, we also found higher abundance of a cold shock protein, CspA, at higher NaCl. We have also identified several other proteins that are differentially exp ...[more]
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