Ontology highlight
ABSTRACT:
SUBMITTER: Lin Q
PROVIDER: S-EPMC4787753 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Lin Qiong Q Chauvistré Heike H Costa Ivan G IG Gusmao Eduardo G EG Mitzka Saskia S Hänzelmann Sonja S Baying Bianka B Klisch Theresa T Moriggl Richard R Hennuy Benoit B Smeets Hubert H Hoffmann Kurt K Benes Vladimir V Seré Kristin K Zenke Martin M
Nucleic acids research 20151017 20
Dendritic cells (DC) are professional antigen presenting cells that develop from hematopoietic stem cells through successive steps of lineage commitment and differentiation. Multipotent progenitors (MPP) are committed to DC restricted common DC progenitors (CDP), which differentiate into specific DC subsets, classical DC (cDC) and plasmacytoid DC (pDC). To determine epigenetic states and regulatory circuitries during DC differentiation, we measured consecutive changes of genome-wide gene express ...[more]