Ontology highlight
ABSTRACT:
SUBMITTER: Oswald F
PROVIDER: S-EPMC4788719 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Oswald Felix F Varadarajan Aravindan A Lill Holger H Peterman Erwin J G EJ Bollen Yves J M YJ
Biophysical journal 20160301 5
The functional organization of prokaryotic cell membranes, which is essential for many cellular processes, has been challenging to analyze due to the small size and nonflat geometry of bacterial cells. Here, we use single-molecule fluorescence microscopy and three-dimensional quantitative analyses in live Escherichia coli to demonstrate that its cytoplasmic membrane contains microdomains with distinct physical properties. We show that the stability of these microdomains depends on the integrity ...[more]