Ontology highlight
ABSTRACT:
SUBMITTER: Antunes NT
PROVIDER: S-EPMC4790369 | biostudies-literature | 2014 Aug
REPOSITORIES: biostudies-literature
Antunes Nuno T NT Fisher Jed F JF
Antibiotics (Basel, Switzerland) 20140821 3
The Class D β-lactamases have emerged as a prominent resistance mechanism against β-lactam antibiotics that previously had efficacy against infections caused by pathogenic bacteria, especially by Acinetobacter baumannii and the Enterobacteriaceae. The phenotypic and structural characteristics of these enzymes correlate to activities that are classified either as a narrow spectrum, an extended spectrum, or a carbapenemase spectrum. We focus on Class D β-lactamases that are carried on plasmids and ...[more]