Ontology highlight
ABSTRACT:
SUBMITTER: Velot L
PROVIDER: S-EPMC4791250 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Velot Lauriane L Molina Angie A Rodrigues-Ferreira Sylvie S Nehlig Anne A Bouchet Benjamin Pierre BP Morel Marina M Leconte Ludovic L Serre Laurence L Arnal Isabelle I Braguer Diane D Savina Ariel A Honore Stéphane S Nahmias Clara C
Oncotarget 20151201 41
The regulation of microtubule dynamics is critical to ensure essential cell functions. End binding protein 1 (EB1) is a master regulator of microtubule dynamics that autonomously binds an extended GTP/GDP-Pi structure at growing microtubule ends and recruits regulatory proteins at this location. However, negative regulation of EB1 association with growing microtubule ends remains poorly understood. We show here that microtubule-associated tumor suppressor ATIP3 interacts with EB1 through direct ...[more]