Ontology highlight
ABSTRACT:
SUBMITTER: Santos G
PROVIDER: S-EPMC4791387 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Santos Guido G Díaz Mario M Torres Néstor V NV
Frontiers in physiology 20160315
A connection between lipid rafts and Alzheimer's disease has been studied during the last decades. Mathematical modeling approaches have recently been used to correlate the effects of lipid composition changes in the physicochemical properties of raft-like membranes. Here we propose an agent based model to assess the effect of lipid changes in lipid rafts on the evolution and progression of Alzheimer's disease using lipid profile data obtained in an established model of familial Alzheimer's dise ...[more]