Ontology highlight
ABSTRACT:
SUBMITTER: Rajagopalan S
PROVIDER: S-EPMC4793721 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Rajagopalan Sumati S Moyle Mark W MW Joosten Irma I Long Eric O EO
Science signaling 20100223 110
Endosomes are emerging as specialized signaling compartments that endow receptors with distinct signaling properties. The diversity of endosomal signaling pathways and their contribution to various biological responses is still unclear. CD158d, which is also known as the killer cell immunoglobulin-like receptor (KIR) 2DL4 (KIR2DL4), is an endosome-resident receptor in natural killer (NK) cells that stimulates the release of a unique set of proinflammatory and proangiogenic mediators in response ...[more]