Ontology highlight
ABSTRACT:
SUBMITTER: Meng F
PROVIDER: S-EPMC4795458 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Meng Fanli F Wang Jiefei J Ge Jian J Fan Xiaopeng X Wang Bing B Han Liyan L Kisseleva Tatiana T Paik YongHan Y Brenner David A DA Wang Kai K
Journal of clinical immunology 20110329 3
<h4>Background</h4>The present study determined type I interferon (IFN) receptor (interferon-α/β receptor (IFNAR)) and its predicable role in interferon-α2b treatment in chronic hepatitis B (CHB) patients.<h4>Methods</h4>Expression of IFN-α/βR-1 and IFN-α/βR-2 in peripheral blood mononuclear cells and in liver tissue was measured by flow cytometry, immunofluorescence, immunohistochemistry and RT-PCR.<h4>Results</h4>IFN-α/βR-1 and IFN-α/βR-2 in monocytes and lymphocytes increased in CHB patients. ...[more]