Ontology highlight
ABSTRACT:
SUBMITTER: Vescovini R
PROVIDER: S-EPMC4798275 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Vescovini Rosanna R Telera Anna Rita AR Pedrazzoni Mario M Abbate Barbara B Rossetti Pietro P Verzicco Ignazio I Arcangeletti Maria Cristina MC Medici Maria Cristina MC Calderaro Adriana A Volpi Riccardo R Sansoni Paolo P Fagnoni Francesco Fausto FF
PloS one 20160318 3
Human cytomegalovirus (HCMV) imprints the immune system after primary infection, however its effect during chronic infection still needs to be deciphered. In this study we report the variation of blood cell count along with anti-HCMV IgG and T cell responses to pp-65 and IE-1 antigens, that occurred after an interval of five years in a cohort of 25 seropositive healthy adults. We found increased anti-viral IgG antibody responses and intracellular interferon-gamma secreting CD8+ T cell responses ...[more]