Ontology highlight
ABSTRACT:
SUBMITTER: Tekin D
PROVIDER: S-EPMC4798889 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Tekin Demet D Yan Denise D Bademci Guney G Feng Yong Y Guo Shengru S Foster Joseph J Blanton Susan S Tekin Mustafa M Liu Xuezhong X
Hearing research 20160202
Extreme genetic heterogeneity along with remarkable variation in the distribution of causative variants across in different ethnicities makes single gene testing inefficient for hearing loss. We developed a custom capture/next-generation sequencing gene panel of 146 known deafness genes with a total target size of approximately 1 MB. The genes were identified by searching databases including Hereditary Hearing Loss Homepage, the Human Genome Mutation Database (HGMD), Online Mendelian Inheritance ...[more]