Ontology highlight
ABSTRACT:
SUBMITTER: Oddo CM
PROVIDER: S-EPMC4798967 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Oddo Calogero Maria CM Raspopovic Stanisa S Artoni Fiorenzo F Mazzoni Alberto A Spigler Giacomo G Petrini Francesco F Giambattistelli Federica F Vecchio Fabrizio F Miraglia Francesca F Zollo Loredana L Di Pino Giovanni G Camboni Domenico D Carrozza Maria Chiara MC Guglielmelli Eugenio E Rossini Paolo Maria PM Faraguna Ugo U Micera Silvestro S
eLife 20160308
Restoration of touch after hand amputation is a desirable feature of ideal prostheses. Here, we show that texture discrimination can be artificially provided in human subjects by implementing a neuromorphic real-time mechano-neuro-transduction (MNT), which emulates to some extent the firing dynamics of SA1 cutaneous afferents. The MNT process was used to modulate the temporal pattern of electrical spikes delivered to the human median nerve via percutaneous microstimulation in four intact subject ...[more]