Ontology highlight
ABSTRACT:
SUBMITTER: Song D
PROVIDER: S-EPMC4800076 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Song Dan D Zhong Yun Y Qian Chunfeng C Zou Qinyan Q Ou Jian J Shi Yichao Y Gao Liang L Wang Gaigai G Liu Zhenxing Z Li Haibo H Ding Hailei H Wu Huihua H Wang Fuxin F Wang Jing J Li Hong H
BioMed research international 20160307
Premature ovarian failure (POF) is one of the most common causes of infertility in women. In our present study, we established cyclophosphamide- (CTX-) induced POF rat model and elucidated its effect on ovarian function. We detected the serum estrogen, follicle stimulating hormone, and anti-Müllerian hormone of mice models by ELISA and evaluated their folliculogenesis by histopathology examination. Our study revealed that CTX administration could severely disturb hormone secretion and influence ...[more]