Dataset Information

Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.

ABSTRACT:

Purpose

Unique features of adolescent cancer patients include cancer types, developmental stages, and psychosocial issues. In this study, we evaluated the relationship between diagnostic delay and survival to improve adolescent cancer care.

Materials and methods

A total of 592 patients aged 0-18 years with eight common cancers were grouped according to age (adolescents, ?10 years; children, <10 years). We retrospectively reviewed their symptom intervals (SIs, between first symptom/sign of disease and diagnosis), patient delay (PD, between first symptom/sign of disease and first contact with a physician), patient delay proportion (PDP), and overall survival (OS).

Results

Mean SI was significantly longer in adolescents than in children (66.4 days vs. 28.4 days; p<0.001), and OS rates were higher in patients with longer SIs (p=0.001). In children with long SIs, OS did not differ according to PDP (p=0.753). In adolescents with long SIs, OS was worse when PDP was ?0.6 (67.2%) than <0.6 (95.5%, p=0.007). In a multivariate analysis, adolescents in the long SI/PDP ?0.6 group tended to have a higher hazard ratio (HR, 6.483; p=0.069) than those in the long SI/PDP <0.6 group (HR=1, reference).

Conclusion

Adolescents with a long SI/PDP ?0.6 had lower survival rates than those with a short SI/all PDP or a long SI/PDP <0.6. They should be encouraged to seek prompt medical assistance by a physician or oncologist to lessen PDs.

SUBMITTER: Jin SL

PROVIDER: S-EPMC4800344 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature

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Publications

Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.

Jin Song Lee SL Hahn Seung Min SM Kim Hyo Sun HS Shin Yoon Jung YJ Kim Sun Hee SH Lee Yoon Sun YS Lyu Chuhl Joo CJ Han Jung Woo JW

Yonsei medical journal 20160501 3

<h4>Purpose</h4>Unique features of adolescent cancer patients include cancer types, developmental stages, and psychosocial issues. In this study, we evaluated the relationship between diagnostic delay and survival to improve adolescent cancer care.<h4>Materials and methods</h4>A total of 592 patients aged 0-18 years with eight common cancers were grouped according to age (adolescents, ≥10 years; children, <10 years). We retrospectively reviewed their symptom intervals (SIs, between first symptom ...[more]

PMID: 26996554

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Dataset Information

Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.

Purpose

Materials and methods

Results

Conclusion

Publications

Symptom Interval and Patient Delay Affect Survival Outcomes in Adolescent Cancer Patients.

Similar Datasets

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