Ontology highlight
ABSTRACT:
SUBMITTER: Yam XY
PROVIDER: S-EPMC4800443 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Scientific reports 20160321
Plasmodium multigene families play a central role in the pathogenesis of malaria. The Plasmodium interspersed repeat (pir) genes comprise the largest multigene family in many Plasmodium spp. However their function(s) remains unknown. Using the rodent model of malaria, Plasmodium chabaudi, we show that individual CIR proteins have differential localizations within infected red cell (iRBC), suggesting different functional roles in a blood-stage infection. Some CIRs appear to be located on the surf ...[more]