Ontology highlight
ABSTRACT:
SUBMITTER: Stella-Ascariz N
PROVIDER: S-EPMC4800466 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Open forum infectious diseases 20160101 1
Archived resistance mutations compromise antiretroviral treatment. We have investigated 3 selected aviremic patients who had extensive historical resistance to their current regimen. All 3 patients underwent unstructured treatment interruptions associated to the re-emergence of wild-type virus before starting their current suppressive regimes. Almost all historical resistance mutations detected in plasma were found in circulating proviral deoxyribonucleic acid. None of the clones analyzed was fu ...[more]