Ontology highlight
ABSTRACT:
SUBMITTER: Binder DC
PROVIDER: S-EPMC4801467 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Binder David C DC Davis Andrew A AA Wainwright Derek A DA
Oncoimmunology 20150911 2
Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and still remains incurable. Although immunotherapeutic vaccination against GBM has demonstrated immune-stimulating activity with some promising survival benefits, tumor relapse is common, highlighting the need for additional and/or combinatorial approaches. Recently, antibodies targeting immune checkpoints were demonstrated to generate impressive clinical responses against advanced melanoma and other malignancies, in ...[more]