Ontology highlight
ABSTRACT:
SUBMITTER: Lulla RR
PROVIDER: S-EPMC4803494 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Lulla Rishi R RR Saratsis Amanda Muhs AM Hashizume Rintaro R
Science advances 20160318 3
Pediatric central nervous system tumors are the most common solid tumor of childhood. Of these, approximately one-third are gliomas that exhibit diverse biological behaviors in the unique context of the developing nervous system. Although low-grade gliomas predominate and have favorable outcomes, up to 20% of pediatric gliomas are high-grade. These tumors are a major contributor to cancer-related morbidity and mortality in infants, children, and adolescents, with long-term survival rates of only ...[more]