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Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.


ABSTRACT: Two molecules of mistaken identity are addressed. Uncovering these assignment errors led us to formulate more general guidelines about additional misassignments in cases of published bis-imines derived from 1,2-phenylenediamine and hydroxybenzaldehydes having no substituent in ortho-positions. The main purpose of this article is to highlight this repetitive assignment error in the literature and thus increase the likelihood of correct assignments in future papers.

SUBMITTER: Reyes-Gutierrez PE 

PROVIDER: S-EPMC4804300 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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Structural revisions of small molecules reported to cross-link G-quadruplex DNA in vivo reveal a repetitive assignment error in the literature.

Reyes-Gutiérrez Paul E PE   Kapal Tomáš T   Klepetářová Blanka B   Šaman David D   Pohl Radek R   Zawada Zbigniew Z   Kužmová Erika E   Hájek Miroslav M   Teplý Filip F  

Scientific reports 20160323


Two molecules of mistaken identity are addressed. Uncovering these assignment errors led us to formulate more general guidelines about additional misassignments in cases of published bis-imines derived from 1,2-phenylenediamine and hydroxybenzaldehydes having no substituent in ortho-positions. The main purpose of this article is to highlight this repetitive assignment error in the literature and thus increase the likelihood of correct assignments in future papers. ...[more]

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