Ontology highlight
ABSTRACT:
SUBMITTER: Srithayakumar V
PROVIDER: S-EPMC4804529 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Srithayakumar Vythegi V Mitchell Gordon B GB White Bradley N BN
BMC veterinary research 20160322
<h4>Background</h4>A clear association of amino acid variation in the prion protein gene (PRNP) with susceptibility and resistance to classical scrapie exists in sheep, but not in goats. In this study we examined DNA sequence variation in the PRNP of 149 animals from two scrapie-infected herds of Saanen dairy goats, and identified 6 non-synonymous variants in the coding region.<h4>Results</h4>In the larger herd, all of the 54 scrapie-affected goats tested had at least one allele with the arginin ...[more]