Associations of air pollution exposure with blood pressure and heart rate variability are modified by oxidative stress genes: A repeated-measures panel among elderly urban residents.
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ABSTRACT:
SUBMITTER: Kim KN
PROVIDER: S-EPMC4807581 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Associations of air pollution exposure with blood pressure and heart rate variability are modified by oxidative stress genes: A repeated-measures panel among elderly urban residents.
Kim Kyoung-Nam KN Kim Jin Hee JH Jung Kweon K Hong Yun-Chul YC
Environmental health : a global access science source 20160325
<h4>Background</h4>Oxidative stress has been suggested as a major cause of elevated blood pressure (BP) and reduced heart rate variability (HRV) due to air pollution. We hypothesized that the associations of air pollution exposure with BP and HRV are modified by oxidative stress gene polymorphisms.<h4>Methods</h4>Between 2008 and 2010, we conducted up to 5 surveys of 547 elderly participants, measured their BP and HRV, and genotyped 47 single nucleotide polymorphisms (SNPs) in 18 oxidative stres ...[more]
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