Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor Cells.
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ABSTRACT:
SUBMITTER: Zeve D
PROVIDER: S-EPMC4807773 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Exercise-Induced Skeletal Muscle Adaptations Alter the Activity of Adipose Progenitor Cells.
Zeve Daniel D Millay Douglas P DP Seo Jin J Graff Jonathan M JM
PloS one 20160325 3
Exercise decreases adiposity and improves metabolic health; however, the physiological and molecular underpinnings of these phenomena remain unknown. Here, we investigate the effect of endurance training on adipose progenitor lineage commitment. Using mice with genetically labeled adipose progenitors, we show that these cells react to exercise by decreasing their proliferation and differentiation potential. Analyses of mouse models that mimic the skeletal muscle adaptation to exercise indicate t ...[more]
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