Ontology highlight
ABSTRACT:
SUBMITTER: Bikoff JB
PROVIDER: S-EPMC4808435 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Cell 20160303 1
Animals generate movement by engaging spinal circuits that direct precise sequences of muscle contraction, but the identity and organizational logic of local interneurons that lie at the core of these circuits remain unresolved. Here, we show that V1 interneurons, a major inhibitory population that controls motor output, fractionate into highly diverse subsets on the basis of the expression of 19 transcription factors. Transcriptionally defined V1 subsets exhibit distinct physiological signature ...[more]