Genetic and treatment-related risk factors associated with external apical root resorption (EARR) concurrent with orthodontia.

ABSTRACT:

Objective

As genetic variation accounts for two-thirds of the variation in external apical root resorption (EARR) concurrent with orthodontic treatment, we analyzed the association of selected genetic and treatment-related factors with EARR concurrent with orthodontic treatment.

Setting and sample population

This case-control study of 134 unrelated, orthodontically treated Caucasian individuals was conducted in part at an Indiana Private Practice, Indiana University and the University of Kentucky.

Methods

Utilizing a research data bank containing information from ~1450 orthodontically treated patients, pre- and post-treatment radiographs from 460 individuals were evaluated for EARR of the four permanent maxillary incisors. Sixty-seven unrelated Caucasians with moderat

SUBMITTER: Sharab LY 

PROVIDER: S-EPMC4810020 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature