The Regulation of NF-?B Subunits by Phosphorylation.
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ABSTRACT:
SUBMITTER: Christian F
PROVIDER: S-EPMC4810097 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Publications
The Regulation of NF-κB Subunits by Phosphorylation.
Christian Frank F Smith Emma L EL Carmody Ruaidhrí J RJ
Cells 20160318 1
The NF-κB transcription factor is the master regulator of the inflammatory response and is essential for the homeostasis of the immune system. NF-κB regulates the transcription of genes that control inflammation, immune cell development, cell cycle, proliferation, and cell death. The fundamental role that NF-κB plays in key physiological processes makes it an important factor in determining health and disease. The importance of NF-κB in tissue homeostasis and immunity has frustrated therapeutic ...[more]
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