Ontology highlight
ABSTRACT:
SUBMITTER: Yang XL
PROVIDER: S-EPMC4810638 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Journal of virology 20151230 6
We report the isolation and characterization of a novel bat coronavirus which is much closer to the severe acute respiratory syndrome coronavirus (SARS-CoV) in genomic sequence than others previously reported, particularly in its S gene. Cell entry and susceptibility studies indicated that this virus can use ACE2 as a receptor and infect animal and human cell lines. Our results provide further evidence of the bat origin of the SARS-CoV and highlight the likelihood of future bat coronavirus emerg ...[more]