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Nucleic acid detection in the diagnosis and prevention of schistosomiasis.

ABSTRACT: Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites are increasing, novel techniques for detection incorporating nucleotide sequences are receiving widespread attention. These sensitive, specific, and rapid detection methods are particularly important in the diagnosis of low-grade and early infections, and may prove to have clinical significance. This paper reviews the progress of nucleic acid detection in the diagnosis and prevention of schistosomiasis, including such aspects as the selection of target genes, and development and application of nucleic acid detection methods.

SUBMITTER: He P

PROVIDER: S-EPMC4812660 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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Nucleic acid detection in the diagnosis and prevention of schistosomiasis.

He Ping P Song Lan-Gui LG Xie Hui H Liang Jin-Yi JY Yuan Dong-Ya DY Wu Zhong-Dao ZD Lv Zhi-Yue ZY

Infectious diseases of poverty 20160330

Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites are increasing, novel techniques for detection incorporating nucleotide sequences are receiving widespread attention. These sensitive, specific, and rapid detection methods are particularly important i ...[more]

PMID: 27025210

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