Ontology highlight
ABSTRACT:
SUBMITTER: Villegas VE
PROVIDER: S-EPMC4813171 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Villegas Victoria E VE Rondón-Lagos Milena M Annaratone Laura L Castellano Isabella I Grismaldo Adriana A Sapino Anna A Zaphiropoulos Peter G PG
International journal of molecular sciences 20160227 3
The selective estrogen receptor (ER) modulator tamoxifen (TAM) has become the standard therapy for the treatment of ER+ breast cancer patients. Despite the obvious benefits of TAM, a proportion of patients acquire resistance to treatment, and this is a significant clinical problem. Consequently, the identification of possible mechanisms involved in TAM-resistance should help the development of new therapeutic targets. In this study, we present in vitro data using a panel of different breast canc ...[more]