Isolation and Expression Analysis of STAT Members from Synechogobius hasta and Their Roles in Leptin Affecting Lipid Metabolism.
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SUBMITTER: Wu K
PROVIDER: S-EPMC4813261 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Isolation and Expression Analysis of STAT Members from Synechogobius hasta and Their Roles in Leptin Affecting Lipid Metabolism.
Wu Kun K Tan Xiao-Ying XY Wei Chuan-Chuan CC You Wen-Jing WJ Zhuo Mei-Qin MQ Song Yu-Feng YF
International journal of molecular sciences 20160322 3
Signal transducers and activators of transcription proteins (STATs) act as important mediators in multiple biological processes induced by a large number of cytokines. In the present study, full-length cDNA sequences of seven STAT members, including some splicing variants different from those in mammals, were obtained from Synechogobius hasta. The phylogenetic analysis revealed that the seven STAT members were derived from paralogous genes that might have arisen by whole genome duplication (WGD) ...[more]
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